Calculation of Efficacy and Futiltiy Boundaries using GrpSeqBnds
نویسنده
چکیده
The function GrpSeqBnds computes efficacy and futility boundaries given the stipulation of the information fraction, total type I and type II error probabilities and method of boundary construction. The efficacy and futility boundaries can be constructed either simulataneously or one at a time. The function also allows for two information scales. The following sequence of variance fractions resulted from a trial with 7 or so years of accrual and maximum follow-up of 20 years using the stopped Fleming-Harrington weights, SFH(0, 1, 10).
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